Error executing setOnClickListener

I can not do a simple BMI calculation. This is the error that appears in the image.

Code:

 ButtonCalcular.setOnClickListener(new View.OnClickListener() {
    @Override
    public void onClick(View view) {

        /* Variáveis que recebem o conteúdo do Edit*/
        String valorPeso   = EdtPeso.getText().toString();
        String valorAltura = EdtAltura.getText().toString();

        if (isCampoVazio(valorPeso) || (isCampoVazio(valorAltura))){

            Toast.makeText(getApplicationContext(), R.string.MSG_Preencher_Campos, Toast.LENGTH_SHORT).show();

        }else{

           double imc =  CalculaImc(Double.parseDouble(valorPeso), Double.parseDouble(valorAltura));
           TextImc.setText(String.valueOf(imc));
        }
    }
}); 

Method that performs the IMC calculation:

//FUNÇÃO QUE FAZ O CÁLCULO DO ÍNDICE DE MASSA CORPORAL
private double CalculaImc(double peso, double altura){

    double resultado = peso/(altura * altura);
    return resultado;
}

Error:

E/AndroidRuntime: FATAL EXCEPTION: main
                  Process: net.ddns.tiyuri.trimc, PID: 14839
                  java.lang.RuntimeException: Unable to start activity ComponentInfo{net.ddns.tiyuri.trimc/net.ddns.tiyuri.trimc.Calcular}: java.lang.NullPointerException: Attempt to invoke virtual method 'void android.widget.Button.setOnClickListener(android.view.View$OnClickListener)' on a null object reference
                      at android.app.ActivityThread.performLaunchActivity(ActivityThread.java:2830)
                      at android.app.ActivityThread.handleLaunchActivity(ActivityThread.java:2905)
                      at android.app.ActivityThread.-wrap11(Unknown Source:0)
                      at android.app.ActivityThread$H.handleMessage(ActivityThread.java:1606)
                      at android.os.Handler.dispatchMessage(Handler.java:105)
                      at android.os.Looper.loop(Looper.java:169)
                      at android.app.ActivityThread.main(ActivityThread.java:6595)
                      at java.lang.reflect.Method.invoke(Native Method)
                      at com.android.internal.os.Zygote$MethodAndArgsCaller.run(Zygote.java:240)
                      at com.android.internal.os.ZygoteInit.main(ZygoteInit.java:767)
                   Caused by: java.lang.NullPointerException: Attempt to invoke virtual method 'void android.widget.Button.setOnClickListener(android.view.View$OnClickListener)' on a null object reference
                      at net.ddns.tiyuri.trimc.Calcular.onCreate(Calcular.java:64)
                      at android.app.Activity.performCreate(Activity.java:7016)
                      at android.app.Instrumentation.callActivityOnCreate(Instrumentation.java:1214)
                      at android.app.ActivityThread.performLaunchActivity(ActivityThread.java:2783)
                      at android.app.ActivityThread.handleLaunchActivity(ActivityThread.java:2905) 
                      at android.app.ActivityThread.-wrap11(Unknown Source:0) 
                      at android.app.ActivityThread$H.handleMessage(ActivityThread.java:1606) 
                      at android.os.Handler.dispatchMessage(Handler.java:105) 
                      at android.os.Looper.loop(Looper.java:169) 
                      at android.app.ActivityThread.main(ActivityThread.java:6595) 
                      at java.lang.reflect.Method.invoke(Native Method) 
                      at com.android.internal.os.Zygote$MethodAndArgsCaller.run(Zygote.java:240) 
                      at com.android.internal.os.ZygoteInit.main(ZygoteInit.java:767) 
I/zygote64: Do partial code cache collection, code=23KB, data=28KB
I/zygote64: After code cache collection, code=23KB, data=28KB
I/zygote64: Increasing code cache capacity to 128KB
I/zygote64: Do partial code cache collection, code=23KB, data=48KB
I/zygote64: After code cache collection, code=23KB, data=48KB
I/zygote64: Increasing code cache capacity to 256KB
I/zygote64: Compiler allocated 8MB to compile void android.widget.TextView.<init>(android.content.Context, android.util.AttributeSet, int, int)