Error Element Reference malformed in signedXml.ComputeSignature

Good morning, I'm newbie to nfe and I'm trying to send the science event of an access key to get the complete xml retrieve the code below the error when I try to call the signedXml.ComputeSignature method. the error only occurs when I define the refer.Uri="# ID210210" + tbchaveAcesso.Text.Trim () + "01"; if set with "" passes normally, the problem is that if I did not understand wrong you have to define it like this. Can anyone help me?

            nfeCabecMsg nfeCabecMsg = new nfeCabecMsg();
            nfeCabecMsg.versaoDados = "1.00";
            nfeCabecMsg.cUF = "91";

            StringBuilder sb = new StringBuilder();

            sb.Append("<envEvento xmlns=\"http://www.portalfiscal.inf.br/nfe\">");
            sb.Append("<versao>1.00</versao>");
            sb.Append("<idLote>000000000000001</idLote>");
            sb.Append("<evento>");
            sb.Append("<versao>\"1.00\"</versao>");
            sb.Append("<infEvento>");
            sb.Append("<id>ID210210" + tbchaveAcesso.Text.Trim() + "01</id>");
            sb.Append("<cOrgao>91</cOrgao>");
            sb.Append("<tpAmb>1</tpAmb>");
            sb.Append("<CNPJ>" + TbCNPJ.Text.Trim() + "</CNPJ>");
            sb.Append("<chNFe>" + tbDanfe.Text.Trim() + "</chNFe>");
            sb.Append("<dhEvento>" + DateTime.Now.ToString("yyyy-MM-ddTHH:mm:sszzz") + "</dhEvento>");
            sb.Append("<tpEvento>210210</tpEvento>");
            sb.Append("<nSeqEvento>1</nSeqEvento>");
            sb.Append("<verEvento>\"1.00\"</verEvento>");
            sb.Append("<detEvento>");
            sb.Append("<versao>\"1.00\"</versao>");
            sb.Append("<descEvento>Ciencia da Operacao</descEvento>");
            sb.Append("</detEvento>");
            sb.Append("</infEvento>");
            sb.Append("</evento>");
            sb.Append("</envEvento>");

            XmlDocument xmlEvento = new XmlDocument();
            xmlEvento.PreserveWhitespace = false;
            xmlEvento.LoadXml(sb.ToString());

            var elementEvento = xmlEvento.GetElementsByTagName("evento")[0];


            var signedXml = new SignedXml(xmlEvento);
            signedXml.SigningKey = certificado.PrivateKey;
            signedXml.SignedInfo.CanonicalizationMethod = SignedXml.XmlDsigExcC14NTransformUrl;
            var refer = new Reference();
           // refer.Uri = string.Empty;
            refer.Uri = "#ID210210" + tbchaveAcesso.Text.Trim() + "01";
            refer.AddTransform(new XmlDsigEnvelopedSignatureTransform());
            refer.AddTransform(new XmlDsigC14NTransform());
            signedXml.AddReference(refer);
            var ki = new KeyInfo();
            ki.AddClause(new KeyInfoX509Data(certificado));
            signedXml.KeyInfo = ki;
            signedXml.ComputeSignature();

TosolvethisproblemIchangedthecreationofxmlto

StringBuildersb=newStringBuilder();

sb.Append("<?xml version=\"1.0\" encoding=\"UTF-8\"?>");
            sb.Append("<envEvento xmlns=\"http://www.portalfiscal.inf.br/nfe\" versao =\"1.00\">");
            sb.Append("<idLote>2</idLote>");
            sb.Append("<evento xmlns=\"http://www.portalfiscal.inf.br/nfe\" versao =\"1.00\">");
            sb.Append("<infEvento Id=\"ID210210" + tbDanfe.Text.Trim() + "01\">");
            sb.Append("<cOrgao>91</cOrgao>");
            sb.Append("<tpAmb>1</tpAmb>");
            sb.Append("<CNPJ>" + TbCNPJ.Text.Trim() + "</CNPJ>");
            sb.Append("<chNFe>" + tbDanfe.Text.Trim() + "</chNFe>");
            sb.Append("<dhEvento>" + DateTime.Now.ToString("yyyy-MM-ddTHH:mm:sszzz") + "</dhEvento>");
            sb.Append("<tpEvento>210210</tpEvento>");
            sb.Append("<nSeqEvento>1</nSeqEvento>");
            sb.Append("<verEvento>1.00</verEvento>");
            sb.Append("<detEvento versao = \"1.00\">");
            sb.Append("<descEvento>Ciencia da Operacao</descEvento>");
            sb.Append("</detEvento>");
            sb.Append("</infEvento>");
            sb.Append("</evento>");
            sb.Append("</envEvento>");

However, although the RS validator is validano successfully, I have rejection msg 225