Use the class System.Security.AccessControl.DirectorySecurity
to request access as an administrator. Applications authenticate to have administrator permissions in this way, not just being run as administrator.
The code should look like this:
string user = "X"; // Troque X pelo nome de usuário de um administrador.
System.IO.DirectoryInfo folderInfo = new IO.DirectoryInfo("C:53323222e00ecf35c7");
DirectorySecurity ds = new DirectorySecurity();
ds.AddAccessRule(New FileSystemAccessRule(user, FileSystemRights.Modify, AccessControlType.Allow));
ds.SetAccessRuleProtection(false, false);
folderInfo.SetAccessControl(ds);
If the above code does not resolve as it is, take a look at the documentation to get the exact permission you need.
Credits - I got the code for this question in the English OS:
Visual Basic .NET Access to the path 'C: \' is denied