How to delete rows from a datagridview

I'm developing a C # program and would like to know how I can block / delete a sql row in datagridview . The line I wanted to delete / block is the last one that is selected in print, I wanted to know if it is possible to block or delete because of to write in that line. I can not also use enable=false; because when I click on datagridview it writes on textbox what is selected