How to configure IIS for its correct operation?

When I run my API through Visual Studio CTRL + F5 or F5 and open my application that consumes this API it works perfectly (both on the same network or through NAT port redirection).

However when I publish, I give publishing, the API works on only one connected device at a time. When I make a request through the browser or the desktop application the android application is put on hold, the same situation when we paused the API, does not launch timeout, however when I exit one of the applications, I close the request process, the other makes the request perfectly ( This scenario does not occur when you are running Visual Studio ). I tried some settings and already checked the .NET version everything is ok.

The code below is the application's web config.

<?xml version="1.0"?>
<configuration>
  <configSections>
    <section name="entityFramework" type="System.Data.Entity.Internal.ConfigFile.EntityFrameworkSection, EntityFramework, Version=6.0.0.0, Culture=neutral, PublicKeyToken=b77a5c561934e089" requirePermission="false"/>
    <!-- For more information on Entity Framework configuration, visit http://go.microsoft.com/fwlink/?LinkID=237468 -->
  </configSections>
  <system.web>
    <compilation targetFramework="4.6.1" debug="true"/>
    <httpRuntime targetFramework="4.6.1"/>
  </system.web>
  <connectionStrings>
   <aqui vem minha conection>
  </connectionStrings>
  <system.webServer>
    <handlers>
      <remove name="ExtensionlessUrlHandler-Integrated-4.0"/>
      <remove name="OPTIONSVerbHandler"/>
      <remove name="TRACEVerbHandler"/>
      <add name="ExtensionlessUrlHandler-Integrated-4.0" path="*." verb="*" type="System.Web.Handlers.TransferRequestHandler" preCondition="integratedMode,runtimeVersionv4.0"/>
      <remove name="WebDAV"/>
      <!--<add name="WebDAV" path="*" verb="*" modules="WebDAVModule" resourceType="Unspecified" requireAccess="None" />-->
    </handlers>
  </system.webServer>
  <runtime>
    <assemblyBinding xmlns="urn:schemas-microsoft-com:asm.v1">
      <dependentAssembly>
        <assemblyIdentity name="System.Web.Helpers" publicKeyToken="31bf3856ad364e35"/>
        <bindingRedirect oldVersion="1.0.0.0-3.0.0.0" newVersion="3.0.0.0"/>
      </dependentAssembly>
      <dependentAssembly>
        <assemblyIdentity name="System.Web.Mvc" publicKeyToken="31bf3856ad364e35"/>
        <bindingRedirect oldVersion="1.0.0.0-5.2.3.0" newVersion="5.2.3.0"/>
      </dependentAssembly>
      <dependentAssembly>
        <assemblyIdentity name="System.Web.WebPages" publicKeyToken="31bf3856ad364e35"/>
        <bindingRedirect oldVersion="1.0.0.0-3.0.0.0" newVersion="3.0.0.0"/>
      </dependentAssembly>
      <dependentAssembly>
        <assemblyIdentity name="Newtonsoft.Json" publicKeyToken="30ad4fe6b2a6aeed" culture="neutral"/>
        <bindingRedirect oldVersion="0.0.0.0-10.0.0.0" newVersion="10.0.0.0"/>
      </dependentAssembly>
      <dependentAssembly>
        <assemblyIdentity name="Microsoft.Owin" publicKeyToken="31bf3856ad364e35" culture="neutral"/>
        <bindingRedirect oldVersion="0.0.0.0-3.1.0.0" newVersion="3.1.0.0"/>
      </dependentAssembly>
      <dependentAssembly>
        <assemblyIdentity name="System.Web.Cors" publicKeyToken="31bf3856ad364e35" culture="neutral"/>
        <bindingRedirect oldVersion="0.0.0.0-5.2.3.0" newVersion="5.2.3.0"/>
      </dependentAssembly>
      <dependentAssembly>
        <assemblyIdentity name="EntityFramework" publicKeyToken="b77a5c561934e089" culture="neutral"/>
        <bindingRedirect oldVersion="0.0.0.0-5.0.0.0" newVersion="5.0.0.0"/>
      </dependentAssembly>
      <dependentAssembly>
        <assemblyIdentity name="Microsoft.IO.RecyclableMemoryStream" publicKeyToken="31bf3856ad364e35" culture="neutral"/>
        <bindingRedirect oldVersion="0.0.0.0-1.2.2.0" newVersion="1.2.2.0"/>
      </dependentAssembly>
      <dependentAssembly>
        <assemblyIdentity name="System.Web.Http" publicKeyToken="31bf3856ad364e35" culture="neutral"/>
        <bindingRedirect oldVersion="0.0.0.0-5.2.3.0" newVersion="5.2.3.0"/>
      </dependentAssembly>
    </assemblyBinding>
  </runtime>
  <entityFramework>
    <defaultConnectionFactory type="System.Data.Entity.Infrastructure.SqlConnectionFactory, EntityFramework"/>
    <!-- <providers> <provider invariantName="System.Data.SqlClient" type="System.Data.Entity.SqlServer.SqlProviderServices, EntityFramework.SqlServer" />  </providers> -->
    <providers>
      <provider invariantName="System.Data.SqlClient" type="System.Data.Entity.SqlServer.SqlProviderServices, EntityFramework.SqlServer"/>
    </providers>
  </entityFramework>
  <system.codedom>
    <compilers>
      <compiler language="c#;cs;csharp" extension=".cs" type="Microsoft.CodeDom.Providers.DotNetCompilerPlatform.CSharpCodeProvider, Microsoft.CodeDom.Providers.DotNetCompilerPlatform, Version=1.0.8.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35" warningLevel="4" compilerOptions="/langversion:6 /nowarn:1659;1699;1701"/>
      <compiler language="vb;vbs;visualbasic;vbscript" extension=".vb" type="Microsoft.CodeDom.Providers.DotNetCompilerPlatform.VBCodeProvider, Microsoft.CodeDom.Providers.DotNetCompilerPlatform, Version=1.0.8.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35" warningLevel="4" compilerOptions="/langversion:14 /nowarn:41008 /define:_MYTYPE=\&quot;Web\&quot; /optionInfer+"/>
    </compilers>
  </system.codedom>
</configuration>
<!--ProjectGuid: 6F0F52CF-412D-4F33-80C9-6A2C9B66B17E-->

The code below is the ASP.NET config.

<?xml version="1.0" encoding="UTF-8" ?>

<configuration>
    <runtime>
        <legacyUnhandledExceptionPolicy enabled="false" />
        <legacyImpersonationPolicy enabled="true"/>
        <alwaysFlowImpersonationPolicy enabled="false"/>
        <SymbolReadingPolicy enabled="1" />
        <shadowCopyVerifyByTimestamp enabled="true"/>
    </runtime>

    <startup useLegacyV2RuntimeActivationPolicy="true" />
</configuration>

The port that is running is 8058.