By preventing an XSS attack (alert (123;)) using the Html.Encode the code on screen is as follows:
<select class="combobox" id="xssSelect" name="cmbXss">
<option selected="selected" value="1"><script>alert(123;)</script></option>
<option value="2">Opcao2</option>
<option value="3">Opcao3</option>
</select>
If you run in IE this combo works perfectly, however in Chrome it hangs and I can not change the options. Give to do this test by the stackoverflow itself executing the code snippet between IE and Chrome.
Note: I'm using Chrome version Version 43.0.2357.81 m
Note2: The stackoverflow itself is preventing XSS attack when I enter the value ... then it follows the value that I am preventing in my image code